Associate Senior Lecturer
Department of Medical Biochemistry and Microbiology (IMBIM)
Uppsala University and SciLifeLab Uppsala, Sweden
Mikael Sellin studied towards a MSc degree at Umeå University and Karolinska Institute and later earned his PhD at the Department of Molecular Biology, Umeå University in 2011. From 2011 until 2015 he was a post-doc at the Institute of Microbiology, ETH Zürich, Switzerland. 2015-2016 he worked as a Senior Scientific Associate at the same department. Since 2016 Mikael Sellin heads a research group at Uppsala University, Department of Medical Biochemistry and Microbiology.
The Sellin lab studies the microbe – host interactions that drive progression of intestinal infectious disease. Instead of exclusively studying the pathogen – host cell interplay under traditional cell culture settings, the Sellin lab aspires to understand the relevant molecular underpinnings under conditions that more closely resemble the intact gut. In this work, the Sellin lab employs organotypic tissue culture, analysis of intact infected tissues, bacterial genetics approaches, and state-or-the-art live microscopy. The work focuses on clinically relevant enteropathogens – i.e. Salmonella and Shigella species – and how these bacteria invade, propagate and spread within the gut mucosa.
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