At GU, infection biology and mucosal immunology have been strong research fields over several decades and these areas have later been complemented with strong microbiome research. Most activities are performed at Sahlgrenska Academy, with close connection with Sahlgrenska University Hospital, the Swedish Dental Service and Region Västra Götaland. GU has world-leading vaccine development of diarrheal diseases with an objective to design new mucosal vaccines that are not delivered by injection. The research focuses on how mucus is formed, how bacteria invade cells and how the immune systems work and the production of new adjuvants to reinforce the immune system for effective vaccination via the mucous membranes. The pathogens targeted by the vaccines cause diseases at the mucous membranes, such as V. cholerae, ETEC and Helicobacter pylori but also includes viral infections, oral infections, and sexually transmitted diseases. At GU in recent years, how the gut microbiota affects the mucus layer and how such interactions affect the infectious process have emerged as strong research fields. Furthermore, this world-leading research also addresses how the gut microbiota may affect inflammation in the gut and cardiometabolic diseases. Much of the research is translational and can thus provide new insights for how to treat these diseases. Details of the research and groups can be found at www.sahlgrenska.gu.se.